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Higher Serum Ferritin Level Associated with Less Cardiovascular Fitness Among Yo
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Paul Kelly
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Dec 29, 2008 10:08 PST
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Low ferritin levels have been hailed as a provenance for RLS for many
years.
This posting is from a doctor in the coronary heart disease usenet group
(called sci.med. cardiology). He is regarded as a bit of a nutter as he
tends to go all religious at times and thus attracts flame wars.
I felt it could not go un-remarked on but leave it to you to make your
own assessment and for others more knowledgeable than I to comment.
"Although iron overload is associated with fatigue and low ferritin is
associated with decreased cardiovascular fitness (CVF), little
research has focused on the relation of elevated ferritin with CVF in
young adult men. An analysis of the National Health and Nutrition
Examination Survey 1999–2002 was conducted to examine the relation
between elevated ferritin and CVF in relatively healthy young adult
men. Adult men aged 20 to 49 years (unweighted n = 1,030, weighted n =
28,514,823) who participated in a treadmill test for CVF were
evaluated. Logistic regressions were computed for ferritin with CVF,
adjusting for age, race or ethnicity, body mass index, anemia,
smoking, exercise, blood donation, and C-reactive protein. Subjects
with ferritin >300 ng/ml were less likely than those with normal
ferritin to have high CVF (odds ratio [OR] 0.57, 95% confidence
interval [CI] 0.32 to 0.99). When ferritin was split into categories,
in a fully adjusted model with a reference group of ferritin at 16 to
100 ng/ml, except for ferritin >100 but <150 ng/ml (OR 0.84, 95% CI
0.65 to 1.08), higher ferritin was associated with a decreased
likelihood of high CVF (>150 but <200 ng/ml: OR 0.55, 95% CI 0.40 to
0.77; >200 but <300 ng/ml: OR 0.49, 95% CI 0.33 to 0.72; >300 ng/ml:
OR 0.40, 95% CI 0.23 to 0.70). The prevalence of ferritin >150 ng/ml
was 45.5% in young adult men. In conclusion, elevated ferritin levels,
even those much lower than what is normally considered to be elevated,
were associated with a decreased likelihood of having high CVF in
young adult men."
Source:
http://www.ajconline.org/article/S0002-9149(08)01456-2/abstract
Eating less, down to the right amount, does result in decreased iron
intake:
http://HeartMDPhDl.com/BeSmart
May dear neighbors, friends, and brethren have a blessedly wonderful
upcoming 2009th year since the birth of our LORD Jesus Christ as our
Messiah, the Son of Man ...
... by being hungrier:
(Lots of religious stuff snipped)
Andrew <><
--
Andrew B. Chung, MD/PhD
Lawful steward of http://EmoryCardiology.com
A latter-day disciple of the KING of kings and LORD of lords.
http://HeartMDPhD.com/WDJW
--
PK
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