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Japanese Cucumber for - Chronic PKD pain
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Tzee Ky
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Nov 03, 2009 08:43 PST
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My opinion:
I eat Japanese cucumber at lease one per day. It helps me to avoid liver cyst Symptoms (pain, heat, itch, swollen, and uncomfortable) in my liver cyst. Japanese cucumber really works for me. My symptom starts from November every year. I went to see my doctor and he referred me to an expert. It did not help at all. Finally, I found the solution - Japaneses cucumber. I see no doctor from that on.
I hope it works for you.
Best Regards,
Tzee Ky
________________________________
From: "jcro-@aol.com" <jcro-@aol.com>
To: pk-@topica.com
Sent: Tue, November 3, 2009 6:41:54 AM
Subject: Re: PKD-PLD Chronic PKD pain
Dear Diane,
At the beginning of my journey with PKD some 14 years ago, I had a lot of cyst ruptures, excruciating pain that would leave me bedridden for days. I was 28 years old. Then, I started reading and searching until I learned about you, the diets and how to change my diet to improve things. Although, I am not 100% vegetarian, I did changed many items of my diet and added some others. I can honestly say that I have not had any pain episodes in years. I can't tell you when was the last time because I truly do not remember.
Both my natives are larger than they were then but I do not have not had any more ruptures or pain. I think for me the secret has been: no red meats, no artificial foods. I also drink nothing but natural juices and water. I do not drink sodas, whole milk or alcohol and I drink a tall glass of cranberry juice every single morning and some afternoons for the last 14 years.
BTW...I am reading The China Project. What an amazing and interesting book. You are living proof that what they found does work. I can wait to finish reading it.
Rgds,
JC
In a message dated 10/29/2009 7:40:33 P.M. Eastern Standard Time, Dia-@pkdiet.com writes:
| | I understand what you are saying JC. Many many years ago, in my hippy days, I traveled extensively throughout Asia, it was so sad to meet up with fellow travelers later after they had become addicted to opium or heroin. They were like walking skeletons.
Opiates happen to be something I cannot take. I just throw up and cannot keep it down. Following my liver resection surgery the docs got very creative on what to give me to relieve pain.
There are several with PKD who have written to me that the only way they can function is by taking opiates to control the daily chronic pain from PKD.
By removing a cystic PKD kidney this has been shown to lessen painful episodes. A very observant surgeon developed a denervation procedure of PKD kidneys as another treatment to lessen severe PKD pain.
There is a PKD pain study underway at the Mayo Clinic with Dr. Marie Hogan that utilizes an interventional procedure known as - Videothracoscopic Splanchnicectomy (VSPL) similar to Videothoracoscopic splanchnicectomy done for pancreatitis pain. For more information on this clinical trial :
http://www.pkdiet.com/pages/pain/painchronic.htm
I too did not realize how difficult and how severe PKD pain can become with some individuals until I went to PKD conference and met with a few individuals using fentanyl patches and more to function.
"FDA announced on February 12, 2008, that PriCara, Division of Ortho-McNeil-Janssen Pharmaceuticals, Inc.has recalled all lots of 25 mcg DURAGESIC® (fentanyl transdermal system) patches sold by PriCara in the United States and all 25 mcg/hr fentanyl patches sold by Sandoz Inc.(See:Sandoz Fentanyl Patch Recall) in the United States are being voluntarily recalled."
At this same PKD conference there was a PKD pain lecture given by both Dr. Torres [giving the medical aspects of PKD pain relief] and the laparoscopic surgeon who developed the denervation procedure. I always learn so much from these conferences, though I have not gone to one since Dr. Torres stopped going.
Warmly,
Diane
On Oct 29, 2009, at 12:23 PM, jcro-@aol.com wrote:
I refused to take Opiates at all cost. Part of my work is working with drug addicted patients and I have seen what Opiates do to a persons life. It literally destroys them physically, financially, mentally and emotionally to the point that they can not function. It is very sad. Do not take them if you can help it. They are extremely addictive.
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Rgds,
JC
In a message dated 10/29/2009 2:40:55 P.M. Eastern Daylight Time, Dia-@pkdiet.com writes:
Some members have chronic pain from PLD and take opiods which can lead to constipation. Here is a new drug to ask your docs about if this applys to you.
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ACG: Compound Eases Constipation for Opioid Patients
By Kristina Fiore, Staff Writer, MedPage Today
Published: October 28, 2009
Reviewed by Zalman S. Agus, MD; Emeritus Professor
University of Pennsylvania School of Medicine and
Dorothy Caputo, MA, RN, BC-ADM, CDE, Nurse Planner
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SAN DIEGO -- An investigational drug increased spontaneous bowel movements for patients with opioid-induced constipation, researchers said here.
Bowel movements per week increased from about one at baseline to five or six, depending on the dose used, Lynn Webster, MD, of Lifetree Clinical Research in Salt Lake City, and colleagues reported at the American College of Gastroenterology meeting here.
The drug, NKTR-118, "increased the frequency of bowel movements without a reversal of analgesia, and it was reasonably safe with no serious problems in this study," Webster said.
He said constipation is a common side effect of opioid therapy, affecting about 40% to 60% of patients on chronic or acute treatments.
The investigational compound is a polymer form of naloxone that antag onizes peripheral opioid receptors in the gut. It can act selectively, preventing it from reversing opioid pain management, the researchers said.
For their Phase-II, randomized, double-blind, placebo-controlled trial, the researchers recruited patients on stable regimens of opioids who consistently had fewer than three spontaneous bowel movements per week.
A total of 208 patients were randomized to either a 5-mg, 25-mg, or 50-mg dose of NKTR-118 or placebo for four weeks.
The researchers found that spontaneous bowel movements increased significantly for patients on the 25-mg and 50-mg dose compared with placebo.
Patients on the 25-mg dose increased to five spontaneous bowel movements per week, up from 1.4 per week at baseline, whereas placebo patients increased to just 3.1 per week from 1.2 at baseline.
Those on the 50-mg dose had six spontaneous bowel movements per week, up from 1.6 at baseline -- a significant improvement compared with those on placebo, who increased to 3.3 per week from 1.4 at baseline.
Spontaneous bowel movements for patients on the 5-mg dose did not differ significantly from those on placebo, the researchers said.
The median time to first bowel movement was 6.6 hours for those in the 25-mg dose, compared with 48.6 hours for those on placebo (P=0.001). It was 2.9 hours for those on the 50-mg dose, compared with 44.9 hours with placebo (P=0.002).
Webster said that there was no change in patient pain, and there were no changes in the amount of opioid used for any patient.
However, dropout rates were significantly higher for the 50-mg dose of the drug compared with placebo, "probably due to the side effect profile," Webster said.
The most sign ificant side effects associated with the drug were gastrointestinal in nature, and included nausea and abdominal pain.
Side effects were not significantly different for the 5-mg dose compared with placebo, and there was more nausea in the placebo group for the 25-mg dose, but side effects were significantly higher in the 50-mg dose compared with placebo.
There was also one serious adverse event in the 50-mg dose, with a patient admitted to the hospital for excessive abdominal cramping.
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