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Fruit Peels May Cut Cholesterol ~ [Issue 0505-1]  Wellness Weekly
 May 03, 2005 09:24 PDT 


A compound found in citrus fruit peels may be more effective than
some prescription drugs at lowering cholesterol, researchers say. The
compounds, called polymethoxylated flavones, can reduce low density
lipoprotein cholesterol without side effects such as liver disease
and muscle weakness, said researchers at the U.S. Department of
Agriculture and Canadian food supplement company KGK Synergize. The
most common citrus PMFs, tangeretin and nobiletin, are found in
tangerine and orange peels, the researchers said. They also are found
in smaller amounts in the juices of these fruits. Using hamster
models with diet-induced high cholesterol, the researchers showed
that feeding them food containing 1 percent PMFs lowered levels of
LDL cholesterol by 32 percent to 40 percent. The compound appears to
work by inhibiting the synthesis of cholesterol and triglycerides
inside the liver. A long-term human study of the effect of PMFs on
high LDL cholesterol is in-progress.
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